There is a caliber called – I kid you not – “22 Wampus Kitty”.
No, there isn’t a Wikipedia entry for it, which makes it an ideal hipster caliber for varmint hunting. (“I shoot gophers with a rifle chambered in 22 Wampus Kitty. It’s a pretty obscure caliber. You’ve probably never heard of it.”)
I found out about this because MidwayUSA actually lists reloading dies for it.
I’m slightly tempted to get something chambered in 22 Wampus Kitty, but: not only would I have to reload it, the process of reloading is complicated.
I’ll stick with .221 Remington Fireball for my hipster cartridge needs, thank you very much.